South Mountain Movement & Wellness

Perineural Injection Therapy

Gentle Relief for Chronic Pain and Nerve Irritation

Perineural Injection Therapy is a natural, non-surgical treatment designed to calm irritated nerves and reduce pain at its source. Using a simple sugar solution (dextrose), these injections are placed just under the skin along the pathways of key nerves. This gentle therapy has been shown to reduce inflammation, block pain signaling, and support natural nerve healing—helping patients find relief and restore function.

How Perineural Injections Work

When nerves become irritated, inflamed, or compressed, they send pain signals that lead to chronic discomfort and restricted movement. Perineural injections address this by:

  • Delivering dextrose solution just beneath the skin, overlying the painful nerves
  • Calming inflammation and nourishing the nerves at a cellular level
  • Interrupting pain signaling so the body can reset and begin healing
  • Supporting the nerves’ natural repair process over time
  • Unlike deeper joint injections, these are very superficial and well-tolerated—making them a gentle yet powerful option for chronic pain.

Benefits of Perineural Injection Therapy

  • Relief from pain caused by irritated or inflamed nerves
  • Improved mobility and function
  • Reduced reliance on pain medications
  • Safe, minimally invasive, and drug-free
  • High success rates reported (80–100% depending on the condition treated)
  • Complements other regenerative therapies such as PRP or Prolotherapy

Conditions Perineural Injections Can Help With

  • Chronic musculoskeletal pain
  • Neck, back, shoulder, or knee pain linked to nerve irritation
  • Sciatica or radiculopathy
  • Whiplash-related pain
  • Post-injury or post-surgical nerve pain
  • Neuralgia and other nerve-based pain syndromes

What to Expect During Treatment

FAQ

They are very superficial and usually well tolerated. Most patients feel only a quick pinch and minimal discomfort.

Relief can last from a few hours to a few days after the first session. With each subsequent treatment, the duration and depth of relief typically improve.

Most patients benefit from a series of 4–6 weekly sessions, with additional follow-ups if needed for long-term conditions.

Because the solution is a simple sugar (dextrose), risks are very minimal. Temporary redness or soreness at the injection site may occur.

Studies and clinical experience show success rates between 80–100%, depending on the condition and patient’s health.

Have More Questions?

Why Choose South Mountain Movement & Wellness for Perineural Injection Therapy?

We integrate perineural therapy with other options—such as PRP, acupuncture, or nutrition counseling—for lasting pain relief and true healing.

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